Protein name:
Endoplasmic reticulum aminopeptidase 2 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Heterodimer with ERAP1.
Function:
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MANSCRKLIF | NIYVVFYCSA | VIMPQICICS | QFTSSPIDQF | NKDPKAFPVA |
100:
TNGEIFPWHE | LRLPTVVIPL | HYDLLIHPNL | TSLDFVASEK | IEVLVRDATQ |
150:
FIILHSKDLE | ILNASLQSEE | DVRYKKPGEN | LTVLSYPAHQ | QIALLVPEKL |
200:
RAHLRYSVAI | DFQAKLADGF | EGFYKSTYRT | LGGETRTIAV | TDFEPTEARM |
250:
AFPCFDEPLF | KANFSIKIRR | ESRHIALSNM | PKVKTIELEG | GLLEDHFETT |
300:
VRMSTYLVAY | IVCDFTSVSG | TASSGVKVSI | YASPDKWSQT | HYALEASVKL |
350:
LDFYENYFDI | HYPLPKLDLV | AIPDFASGAM | ENWGLITYRE | TSLLFDPKTS |
400:
STSDKLWVTK | VIAHELAHQW | FGNLVTMEWW | NDIWLNEGFA | RYMELISLNI |
450:
TYPELQFDDS | FSNTCFEVIK | RDSLNSSHPI | SNEAKTATQI | KEMFDAVSYN |
500:
KGACILNMLK | DFLSEETFRK | GIIHYLKKFT | YRNAKNDDLW | HSLSNNCLEG |
550:
DSTSGGFCYS | DSRKTSNTLA | FLRENVELKE | MMATWTLQKG | IPLVVVKREG |
600:
RSLRLQQERF | LSGVFKEDPE | WGTLQERYLW | HIPVTYSTSS | SQAIHRHILK |
650:
LKTDTVDLSE | KTDWVKFNVD | SSGYYIVHYE | GQGWDELITL | LNQNHTLLRP |
700:
KDRLGLIHDA | FQLVSAGRLT | LDKALDLTRY | LQHETSIPAL | LKGLEYLELF |
750:
YRMVERRNIS | DVTENLKHYL | LQYFKPVIDT | QSWLDEGSVW | DRMLRSTVLK |
800:
LACYLNHAPC | IQKATELFSQ | WMESSGKLNI | PADVLTIVYS | VGAQTTAGWN |
850:
YLLEQYELSL | SGAEKNKILY | ALSTSKHQEK | LMKLIELGME | GKVIKTQDLA |
900:
TLLFTTARNP | KGQQLAWNFV | KENWTHLLKK | FELGSFPIRM | IISGTTSHFS |
950:
SKDELQEVKL | FFESLKAQGS | HLDIFQIILE | TISKNIKWLE | KNLPTLRKWL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
ELISA Kit for Bovine Endoplasmic reticulum aminopeptidase 2
ELISA Kit for Bovine Endoplasmic reticulum aminopeptidase 2
CLIA Kit for Bovine Endoplasmic reticulum aminopeptidase 2
CLIA Kit for Bovine Endoplasmic reticulum aminopeptidase 2
Polyclonal Antibody for Bovine Endoplasmic reticulum aminopeptidase 2
Polyclonal Antibody for Bovine Endoplasmic reticulum aminopeptidase 2
Monoclonal Antibody for Bovine Endoplasmic reticulum aminopeptidase 2
Monoclonal Antibody for Bovine Endoplasmic reticulum aminopeptidase 2
Protein for Bovine Endoplasmic reticulum aminopeptidase 2
Protein for Bovine Endoplasmic reticulum aminopeptidase 2
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Thymus .